Research > Team II:Structure-Based Drug Design Discovery

Name Jianping Lin
Research Area  Simulation of complex biosystem
 Developing drug design methods including coarse-grained docking, target indentification methods, in silico screening
Tel 0086-22-23506290
Jianping Lin received a BS degree in Chemistry from Beijing University, Beijing, China, in 1997, a MS degree in Chemistry from Beijing University, Beijing, China, in 2000, and a PhD degree from Duke University, Durham, the United States in 2005, in Theoretical Biophysics and Biochemistry. Having completed his postdoctoral training in Beckman Research Institute, City of Hope Medical Center, USA, he joined the faculty of Nankai University, Tianjin, in 2009. He is currently a Professor in the College of Pharmacy
Resent Publications (in 5 years)
1.             Lin J; Beratan DN “Simulation of Electron transfer between Cytochrome c2 and the Bacterial Photosynthetic Reaction Center: Brownian Dynamics Analysis of the Native Proteins and Double Mutants.   J. Phys. Chem. B 2005, 109, 7529-7534.
2.             Lin J, Balabin IA, Beratan DN. The Nature of Aqueous Tunneling Pathways between Electron-transfer Proteins. Science 2005, 310,1311-1313.   related news: “Water can ease electron transfer between proteins” Chemical & Engineering NewsNovember 28, 2005. Page 11.
3.             Lin J, Seeman NC, Vaidehi N. Molecular dynamics simulations of insertion of chemically modified DNA nanostructures into water-chloroform interface. Biophys J. 2008 Aug,95(3),1099-107.
4.             Lin J, Buettner R, Yuan YC, Yip R, Horne D, Jove R, Vaidehi N. Molecular dynamics simulations of the conformational changes in Signal Transducers and Activators of Transcription, Stat1 and Stat3. J Mol Graph Model. 2009 Nov,28(4),347-56.
5.             Lin J*, Liu P, Yang HZ, Vaidehi N*. Factors That Affect the Computational Prediction of Hot Spots in Protein-Protein Complexes, Comput. Mole. Sci. 2012, 2, 23-34.