Research > Team II:Structure-Based Drug Design Discovery

Name Gang Bai
Research Area Systems Biology of Traditional Chinese Medicine (TCM)
(1) target-based active ingredients screening;
(2) bioactivity-integrated UPLC-QTOF identification;
(3) chemical modification of active ingredients and protein target fishing;
(4) analysis of action mechanism of TCM
(5) the compatibility of TCM
Tel 0086-22-23506792
Gang Bai obtained a BS degree in Pharmacy from Shenyang Pharmaceutical University, Shenyang, China, in 1990, and a PhD degree from Nagasaki University, Nagasaki, Japan in 1998, also in Pharmacy. After completing his PhD, he joined Bio-Clean System Co., Ltd. in Japan as a Senior Researcher. He moved back to China in 2000 as an Associate Professor of Microbiology in College of Life Sciences,Nankai University, followed by professorship in 2002. He is a Professor of Pharmacognosy in the College of Pharmacyat Nankai University since 2007.
Resent Publications (in 5 years)
1.     Z Gao, Q Zhang, Y Cao, P Pan,  F Bai,  G Bai*.Preparation of novel magnetic cellulose microspheres via cellulose binding domain-streptavidin linkage and use for mRNA isolation from eukaryotic cells and tissues.J Chromatogr A 2009, 1216(45):7670-6.
2.     Y Tang, Q Zhang, L Wang, PW Pan, G Bai*. Preparation of cellulose magnetic microspheres with "the smallest critical size" and their application for microbial immunocapture.Langmuir 2010, 26(13):11266-71
3.     Q Shi, YHou, JHou, P Pan, Z Liu, M Jiang, J Gao, G Bai*. Glycyrrhetic acid synergistically enhances β2-adrenergic receptor-Gs signaling by changing the location of Gαs in lipid rafts. PLoS One 2012, 7(9): e44921
4.     PW Pan, Q Zhang, JHou, Z Liu, F Bai, MR Cao, T Sun, G Bai*.Cell surface glycoprotein profiling of cancer cells based on bioorthogonal chemistry. Anal Bioanal Chem2012, 403(6):1661-70
5.     YHou, X Cao, L Dong, L Wang, B Cheng, Q Shi, X Luo,G Bai*.Bioactivity-based liquid chromatography-coupled electrospray ionization tandem ion trap/time of flight mass spectrometry for β2AR agonist identification in alkaloidal extract ofAlstoniascholaris. J Chromatogr A 2012, 1227:203-9