Research > Team III:Drug Delivery Bio-Analysis & Bio-Imaging



Name Deming Kong
Research Area The design of chemical sensors and biosensors on the basis of DNAzymes
The design and screening of specific G-quadruplex ligands
Tel 0086-22-23500938
E-mail kongdem@nankai.edu.cn
Brief
Introduction
DemingKong obtained a BS degree in Chemistry from Nankai University, Tianjin, China, in 1998, and a PhD degree in Analytical chemistryfrom Nankai University in 2003. In this year, he joined the College of Chemistry in Nankai University as anassistant professor, and was promoted to associate professor in December 2004, and to professor in December 2009. As a visiting scholar, he worked in Kent State University (USA) for half a year (January 2014~July 2014). He won the Second Prize of the Natural Science of Tianjin (second place) in 2008, Chinese Chemical Society Young Chemist Award in 2010, and New Century Excellent Talents in University in 2010.In 2014, he won the support of theExcellent Young Scientist Fundation of NSFC.
Resent Publications (in 5 years)
1.      Zhang,Li, H, Kong, D-M, Shen,H-X, Sensitive dual DNAzymes-based sensors designed by grafting self-blocked G-quadruplexDNAzymes to the substrates of metal ion-triggered DNA/RNA-cleaving DNAzymes. BiosenBioelectron 2012; 38: 331-6.
2.      Cai, Y, Li, N, Kong, D-M, Shen,H-X,Fluorogenic substrate screening for G-quadruplex DNAzyme-based sensors. BiosenBioelectron 2013; 49: 312-317.
3.      Huang,X-X, Zhu,L-N, Wu,B, Huo, Y-F, Duan,N-N, Kong, D-M, Two cationic porphyrin isomers showing different multimeric G-quadruplex recognition specificity against monomeric G-quadruplexes. Nucleic Acids Res 2014;42:8719-31.
4.      Zhang, Q, Song, C, Zhao, T, Fu, H-W, Wang, H-Z, Wang, Y-J, Kong, D-M,Photoluminescent sensing for acidic amino acids based on the disruption of graphene quantum dots/europium ions aggregates. BiosenBioelectron 2015; 65: 204-210.
5.      Jiang, H-X, Cui, Y, Zhao, T, Fu, H-W, Koirala, D, Punnoose, JA,Kong, D-M, Mao, H, Divalent cations and molecular crowding buffers stabilize G-triplex at physiologically relevant temperatures.Sci Rep 2015;5:9255.