Research > Team I:Molecular Mechanisms of Diseases and Target

Name Jihong Han
Research Area Vascular biology, lipid metabolism and cancer
Tel 0086-22-23500522
Jihong Han obtained his BS and Master degrees in Chemistry from Nankai University, Tianjin, China, in 1987 and 1989, respectively. He then finished his PhD degree in Biochemistry in the Medical College of Cornell University, New York, United States, in 1995. After his postdoctoral training, he joined the faculty of Cornell University Medical College in New York in 1999 as an Assistant Professor of Pathology. In 2004, he was promoted toan Associate Professor of Pathology in the same institute. He moved his laboratory to China in 2007 and joined the faculty of Nankai University, Tianjin. Currently, he is a Professor and an Associate Dean of the College of Life Sciences at Nankai University.
Resent Publications (in 5 years)
1.      Ma X, Liu Y, Wang Q, Chen Y, Liu M, Li X, Xiang R, Wei Y, Duan Y, Han J*. 2015. Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression. BBA-Molecular Basis of Diseases. 1852:1038-1048.
2.      Chen Y, Duan Y, Yang X, Sun L, Liu M, Wang Q, Ma X, Zhang W, Li X, Hu W, Miao QR, Xiang R, Hajjar DP, Han J*. 2015. Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in apoE deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology. 35:948-959.
3.      Ma X, Wang Q, Liu Y, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao RQ, Duan Y, Han J*. 2015. Inhibition of tumor growth by U0126 is associated with induction of interferon-gproduction. International Journal of Cancer, 136:771-783.
4.      Wang Q, Ma X, Chen Y, Zhang L, Jiang M, Li X, Xiang R, Miao R, Hajjar DP, Duan Y, Han J*. 2014. Identification of interferon-g as a new molecular target of liver X receptor. Biochemical Journal. 459:345-354.
5.      Jiang M, Zhang L, Ma X, Hu W, Chen Y, Yu M, Wang Q, Li X, Yin Z, Zhu Y, Gao X, Hajjar DP, Duan Y, Han J*. 2013. Tamoxifen inhibits macrophage FABP4 expression through the combined effects of GR and PPARg pathways. Biochemical Journal.454:467-477