Research > Team I:Molecular Mechanisms of Diseases and Target

Name Zhangyong Hong
Research Area Protein and peptide drugs 
Vaccine development
Photodynamic therapy


1992-1997  B.S. in Chemistry, University of Science and technology of China
1997-2002  Ph.D. in Organic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science

Professional Experiences:

2003-2009   Research Associate in Molecular Biology and Glycobiology, Department of Chemical biology, The Scripps Research Institute, CA, USA
2009-present  Professor, College of Life Sciences, State Key Lab of Medicinal Chemical Biology, Nankai University

Resent Publications (in 5 years)
1.     M. Yu, Z. Chen, W. Guo, J. Wang, Y. Feng, X. Kong, Z. Hong. Specifically targeted delivery of protein to phagocytic macrophages. Int. J. Nanomed., 2015, 10, 1743-1757.
2.     R. Tian, M. Li, J. Wang, M. Yu, X. Kong, Y. Feng, Z. Chen, Y. Li, W. Huang, W. Wu, Z. Hong. An Intracellularly Activatable, Fluorogenic Probe for Cancer Imaging. Org. Biomol. Chem., 2014, 12, 5365-5374 (Cover story).
3.     Y. Li, Y. Li, M. Pan, X. Kong, Y. Huang, Z. Hong, L. Liu. Irreversible Site-Specific Hydrazinolysis of Proteins by Use of Sortase. Angew. Chem., Int. Ed. 2014, 53, 2198-2202.
4.     X. Kong, K. Yu, M. Yu, Y. Feng, J. Wang, M. Li, Z. Chen, M. He, R. Guo, R. Tian, Y. Li, W. Wu, Z. Hong, A novel multifunctional poly(amidoamine) dendrimeric delivery system with superior encapsulation capacity for targeted delivery of the chemotherapy drug 10-hydroxycamptothecin, Int. J. pharm., 2014, 465-378-387.
5.     M. He, L. Zhang, L. Sun, X. Wang, X. Jing, D. Du, H. Liang, M. Liu, Z. Hong, J. Zhou. Systematic analysis of the functions of lysine acetylation in the regulation of Tat activity. Plos one, 2013, 27, 8, e67186.