Research > Team I:Molecular Mechanisms of Diseases and Target



Name Shouguang Jin
Research Area Regulation of bacterial virulence factors and mechanisms of antibiotic resistance
Develop an efficient genome editing tool from a bacterial protein injection system
Tel 0086-22-23507008
E-mail nksjin@nankai.edu.cn
Brief
Introduction
ShouguangJin obtained a BS degree in Microbiology from Nankai University, Tianjin, China, in 1984, and a PhD degree from University of Washington, Seattle, United States in 1990, also in Microbiology. Having completed his postdoctoral training at University of Washington, he joined University of Arkansas medical school in 1993 as an assistant professor. In 1995, he joined Department of Molecular Genetics and Microbiology, University of Florida Medical School, and was promoted to professor in 2005. He moved his laboratory to China in 2010. In the same year, he was selected in the 1,000 Talents Plan China. He is currently a professor of Microbiology in the Department of Microbiology, College of Life
Resent Publications (in 5 years)
1.          Bichsel C, Neeld D, Hamazaki T, Chang LJ, Yang LJ, Terada N, Jin S. (2013) Direct reprogramming of fibroblasts to myocytes via bacterial injection of MyoDprotein.CellReprogram. 15(2):117-25.
2.          Li K, Xu C, Jin Y, Sun Z, Liu C, Shi J, Chen G, Chen R, Jin S, Wu W (2013). SuhB Is a Regulator of Multiple Virulence Genes and Essential for Pathogenesis of Pseudomonas aeruginosa. MBio. 29;4(6). doi:pii: e00419-13. 10.1128/mBio.00419-13.
3.          Kim, Y-J., J-H. Lee, Y. Lee, J. Jia, S-H. Paek, H-B. Kim, S. Jin, U-H Ha. (2014) Nucleoside diphosphate kinase and flagellin from Pseudomonas aeruginosa induce interleukin 1 expression via the Akt/NF-B signaling pathways. InfectImmun 82:3252-60.
4.          Neeld, D., Y. Jin, C. Bichsel, J. Jia, J. Guo, F. Bai, W. Wu, U-H. Ha, N. Terada and S. Jin. (2014) Pseudomonas aeruginosa injects NDK into host cells through a type III secretion system.Microbiol 160:1417-26.
5.          Jia J, Y. Jin, T. Bian, D. Wu, L. Yang, N. Terada, W. Wu and S. Jin. (2014) Bacterial delivery of TALEN proteins for human genome editing. PLoS One 9(3):e91547.