Research > Team I:Molecular Mechanisms of Diseases and Target

Name Yao Chen
Research Area 1. Fermentation to produce multifunctional peptide vectors as novel and high efficient gene/protein/small-molecule drug delivery system
2. Using metalloprotein inhibitors as targets, developing antibiotics and antimicrobial agents through Fragment-based drug discovery strategy
3. Investigating the influence of environment pollution towards cellular metal homeostasis using elemental mapping
4. Biomimetic and biocatalysis application of porous materials, e.g. Metal-Organic Framework
Study and work experience:
2002-2006, B.S. in Pharmaceutical Engineering, Qingdao University of Science and Technology, China,
2006-2008, M.S. in Microbiology, Nanjing University of Technology, China,
2008-2010, M.S. in Chemical Engineering, Ohio University, USA,
2011-2014, Ph.D. in Chemistry, University of South Florida, USA)
2014.7-2016.7,UC San Diego, department of chemistry and biochemistry, postdoctoral fellow
Research contents:
Research in Chen laboratory has focused on:Gene, protein and small molecule drug delivery; Development of novel antimicrobial material and antibiotic; Discovery and evaluation of metalloprotein inhibitors; The biomedical and biocatalysisapplication of porous materials. She has published original research articles in J. Am. Chem. Soc., Angew. Chem., J. Med. Chem., ChemMedChem, andInorg.Chem.among others.
Resent Publications (in 5 years)